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Custom Synthesis

                                 

Challenges We Solve

Challenges
Solutions
Typical Case
High cost, low yield from literature routes
Free route evaluation, provide 2-3 alternative routes comparison
A pyrimidine intermediate: literature yield 12% → optimized to 41%
Tight deadline, standard supply lead time 3+ months
Fast-track: feasibility verification within 14 working days
A chiral amine: from inquiry to delivery of 500g only 5 weeks
New structure, no existing intermediates available
From concept at milligram scale to product at kilogram scale
Complex fused-ring compound delivered with 99.2% purity
Confidentiality concerns
Strict CDA/NDA + project isolated + final delivery without impurity data
All projects protected under independent access & tracking system

Representative Deliveries

Each molecule tells a story of collaboration — from your inquiry to our delivery.

PDE7-IN-3 | CAS No.:908570-13-8 | Chiral purity 99.5% | 120g | 6 weeks | Inhibitor Intermediate
BGP-15 | CAS No.:66611-37-8 |purity ≥98% | 500g | 4 weeks | Pharmaceutical Intermediate
L-DON | CAS No.:157-03-9 |purity ≥99% | 20g | 2 weeks | Chiral Building Block
BI8626 | CAS No.:1875036-75-1 |purity ≥99% | 10g | 4 weeks | Inhibitor Intermediate
HN37 | CAS No.:1821222-10-9 |purity ≥99% | 10g | 4 weeks | Chiral Building Block

Custom Synthesis Service Process

1

Requirements Communication & Feasibility Assessment

Customer provides target structure, purity, quantity, lead time. Our PM & R&D review technical difficulties, cost, compliance. Sign CDA/NDA as required.

2

Route Design & Pilot Planning

Design multiple routes, optimize based on green chemistry. Evaluate reagents, solvents, catalysts, economic feasibility, supply chain lead time.

3

Laboratory Small Scale (GLP Environment)

Conduct small scale synthesis to validate route feasibility. Continuously optimize reaction conditions, yields, purification methods.

4

Pilot / Scale-Up & GMP Production

Enter pilot or small batch GMP production (kg to kg grade). Ensure CMC specifications are met under GMP workshop.

5

Quality Control & Documentation

Production records → Critical parameter confirmation → QC data → COA. Provide complete batch documentation.

6

Product Delivery & Follow-Up Support

Package and ship compounds (solid, solution, lyophilized). Provide ongoing process support, batch adjustment, tech transfer.

Custom Synthesis
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